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| S.No | Product Name | Intermediate | CAS No | Therapeutic Use |
|---|---|---|---|---|
| 1 | Aripiprazole | 7-hydroxy-3,4-dihydroquinolin-2-one | 22246-18-0 | Antipsychotic |
| 7-(4-Bromobutoxy)-3,4-dihydroquinolin -2-one | 129722-34-5 | |||
| 1-(2,3- Dichloro phenyl) pipearzine hydrochloride | 119532-26-2 | |||
| 2 | - | α-(-4-Chlorophenyl) pyridine -2-methanol | 27652-89-7 | - |
| 4-Hydroxypiperidine | 5382-16-1 | |||
| 3 | Brigatinib | 1-methyl-4-(piperidin-4-yl)-piperazine | 53617-36-0 | small-molecule targetd cancer therapy |
| 4 | Crizotinib | N-Boc-4-hydroxy piperidine | 109384-19-2 | Antineoplastic |
| 5 | Dabigatran Etexilate Mesylate | 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester | 211915-84-3 | Antithrombotic |
| N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine ethyl ester | 429658-95-7 | |||
| Ethyl 3-(((2-(((4-((((hexyloxy) carbonyl) amino) iminomethyl) phenyl) amino)\methyl)-1-methyl-1H-benzimidazol-5-yl)\carbonyl)(pyridin-2-yl)amino) propanoate | 211915-06-9 | |||
| 6 | Domperidone | 1-(3-Chloropropyl)-1,3-dihydro-1H-benzimidazol-2-one | 62780-89-6 | Antiemetic |
| 5-Chloro 1,3 dihydro -1- (4-piperidinyl) -2H- benzimidazol - 2 -one | 53786-28-0 | |||
| 7 | Donepezil | 4-[(5,6-Dimethoxy-1-indanon-2-yl) methyl] piperidine | 120014-30-4 | Nootropic |
| 5,6-dimethoxy-2-(pyridine-4-yl)-methylene-indan-1-one | 4803-74-1 | |||
| 8 | Eprosartan | 2-Butyl-4-formalimidazole | 68282-49-5 | Antihypertensive |
| 9 | Febuxostat | Ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate | 161797-99-5 | Antihyperuricemic |
| Ethyl 2-(3-formyl-4-hydroxypheip)-4-methylthiazole-5-carboxylate | 161798-01-2 | |||
| Ethyl 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate | 161798-02-3 | |||
| Ethyl-2-(3-Formyl-4-isobutoxy phenyl)-4-methyl-1,3-thiazole-5-carboxylate | 161798-03-4 | |||
| Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate | 160844-75-7 | |||
| 9 | Golvatinib & Gilteritinib | 1-N-Methyl-4-(4-piperidin-4-yl)-piperazine | 53617-36-0 | Anticancer |
| 10 | Linagliptin | (R)-3-(boc-amino) piperidine | 309956-78-3 | Antidiabetic |
| (R)-3-Piperidinamine dihydrochloride | 334618-23-4 | |||
| 11 | Loperamide HCl | 4-(4-Chlorophenyl)-4-hydroxy piperidine | 39512-49-7 | Antidiarrheal |
| N,N-Dimethyl(tera hydro-3,3-diphenyl)-2-furyliden ammonium bromide ( furanuminium bromide ) | 37743-18-3 | |||
| 1,1-Diphenyl-3-butyrolactone | 956-89-8 | |||
| 4-Bromo-2-2-diphenylbutyric acid | 37742-98-6 | |||
| 12 | Loratadine | 3-[2-(3Chlorophenyl) ethyl)-2-cyano pyridine (or) 3-[2-(3-Chlorophenyl)–ethyl]–2–pyridine carbonitrile (Cyano compound) | 31255-57-9 | Antihistaminic |
| 8-Chloro-5,6 dihydro(11H)-benzo[5,6] cyclohepta (1,2b) pyridine -11-one | 31251-41-9 | |||
| 8 Chloro-11-[(N-methyl)-4-piperidylidene]-6, 11-dihydro-5H-benzo [5,6]cyclohepta (1,2b) pyridine (methyl loratadine) | 38092-89-6 | |||
| {3-[2-(3-Chlorophenyl)ethyl]pyridine-2-yl}-(1-methyl piperidine-4-yl) (methonal HCL) | 119770-60-4 | |||
| 13 | Mirabegron | (R)-N-(4-nitrophenethyl)-2-hydroxy-2-phenylacetamide | 521284-19-5 | Over active bladder |
| (R)-2-(4-nitrophenethylamino)-1-phenylethanol.HCl | 521284-21-9 | |||
| (R)-2-(4-aminophenethylamino)-1-phenylethanol | 521284-22-0 | |||
| 14 | Prucalopride | 1-(3-Methoxy propyl) piperidine-4-one | 16771-85-0 | Gatroprokinetic |
| 1-(3-Methoxypropyl)-4-Piperidinamine | 179474-79-4 | |||
| 15 | Rifabutin | 1-Isobutyl-4-piperidone | 72544-16-2 | Antibactrerial |
| 16 | Rivaroxaban | 4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone | 446292-08-6 | Antithromobotic |
| 4-(4-((S)-5-(Aminomethyl)-2-oxooxazolidin-3-Yl) phenyl)morpholin-3-one HCl | 898543-06-1 | |||
| 17 | Ropivacaine | (S)-N-(2,6-Dimethylphenyl)piperidine-2-carboxamide | 27262-40-4 | Anaesthesia |
| 18 | Rupatadine Fumarate | 3-Chloromethyl-5-methyl pyridine HCl | 1007089-84-0 | Antihistaminic |
| 19 | Selexipag | 4-(Isopropylamino)butanol | 42042-71-7 | Antihypertensive |
| 20 | Tamsulosin | R-(-)-5-(2-Amino-propyl)-2-methoxy-benzenesulfonamide | 112101-81-2 | in treatment of benign prostatic hypertrophy |
| 5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide | 106133-20-4 | |||
| 21 | Trazadone | [1,2,4]triazolo[4,3-a]pyridin-3-one | 6969-71-7 | Antidepressant |
| "1-(3-chlorophenyl)-4-(3-chloropropyl) piperazine hydrochloride" | 52605-52-4 | |||
| 22 | Trimeperidine | 1,2,5 trimethyl-4-Piperidone | 7516-33-8 | Antianalgesic |
| 23 | Vonoprazan Fumarate (VOF) | 5-(2-Fluorophenyl)-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-carboxaldehyde | 881677-11-8 | Astric ulcer, duodenal ulcer and reflux esophagitis |
| 24 | Pemetrexed | 4-[2-(2-AMINO-4,7-DIHYDRO-4-OXO-1H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)ETHYL] BENZOIC ACID | 137281-39-1 | Cancer |
| 25 | FELBAMATE | 2-phenyl 1,3 propanediol | 1570-95-2 | Anticonvulsant (Epilepsy) |
| 26 | - | N-(4-AMINO-2-CYANOPHENYL)-N,N-DIMETHYLMETHANIMIDAMIDE | 194423-17-1 |